The 6 panels plot index scores v. θ for the 5 main health-related quality-of-life (HRQoL) indexes and the Health Activities Limitations Index (HALex). Horizontal and vertical banding for the 3844 data points in each plot represents discrete attainable levels for the index or derived θs. The heavy lines are points fit using Minitab®15.1 statistical software and the locally weighted scatterplot smoothing (LOWESS) option, a variant of kernel smoothing in the vertical dimension of scatterplots. The LOWESS lines demonstrate nonlinearity of the relation between the index scales and θ.
The six panels plot index scores versus Relative θ for the 5 main HRQoL indexes and the HALex. The heavy lines are points fit using Minitab®15.1 statistical software and the locally weighted scatterplot smoother (LOWESS) option.
Statistical analysis, in terms of descriptive statistics, P-Value of concordance test and P-Value of correlation, has been performed with MINITAB 15.1 software. Logistic regression tool available in the software was adopted to investigate the relationship between a response variable and one or more predictors when ordinal and/or nominal categories were of interest.
Two-Sample T-Tests and non-parametric Mann-Whitney tests were performed, all at the 1% significance level, to compare the rate of nucleotide misincorporation (m) between: (a) ancient and modern sequences, (b) ancient and putative contaminant sequences and (c) modern and putative contaminant sequences. The tests allowed us to accept or reject the null hypothesis (H0) that the m values of the three classes of sequences are the same. To highlight the distribution of m among the three classes of sequences, the rate of nucleotide misincorporation for each of them was represented using a box-plot. The statistical analysis was performed using the Minitab 220.127.116.11 software.
Two sample T-Test and non-parametric Mann-Whitney tests were performed at the 1% significance level to assess the statistical significance of nucleotide misincorporation in ancient and modern sequences. We also plotted the nucleotide misincorporation number for each transition and transversion complementary group for ancient and modern sequences. In this case too, the statistical analysis was performed using the Minitab 18.104.22.168 software. 2b1af7f3a8